Boris Johnson has sought to rally his senior ministers at a cabinet meeting, after surviving a vote to oust him as Conservative Party leader.
He was backed by 211 Tory MPs in the confidence vote triggered by anger over Partygate but 148 voted to remove him.
The number of rebels was higher than had been predicted and ex-Tory leader William Hague has advised him to quit.
Addressing his cabinet, Mr Johnson said it was time to "draw a line" under the row about his leadership.
He said the government would be focusing exclusively on issues "people want" such as "dealing with the aftershocks of Covid" and rising energy prices.
The prime minister also urged his ministers to look at ways of "cutting regulations adding that there was "ample scope" for the government "to get out of peoples' way".
Under Conservative Party rules, the prime minister now cannot face another confidence vote for one year.