The US will no longer require air travellers to have proof of a negative Covid-19 test before entering the country from abroad.
Officials said they were dropping the requirement due to the "tremendous progress" the country had made in the fight against the virus.
The travel industry has been pushing for an end to the policy, which they say has deterred bookings, as families fear getting stranded abroad.
The change comes into effect on Sunday.
The Centers for Disease Control and Prevention (CDC) will re-evaluate the policy in 90 days. The administration said it would "not hesitate to act" to reinstate the rule should new variants make officials believe it is necessary.