**** SPOILERS IF YOU ARE NOT UP TO DATE ON THE BOYS TV SHOW ****
The Boys season 3's V-24 storyline perfectly flips Hughie and Butcher's roles from the comics, turning a crucial moment into something darker.
During their mission to locate "BCL Red," Hughie realizes Butcher is doping with V-24 and begs for a hit himself.
Butcher refuses the request, telling Hughie he's better than sinking to such a grim level, but Starlight's frustrated boyfriend goes behind Butcher's back and takes a dose regardless.
The complete opposite transpires in The Boys' comic books. Here, Hughie has only recently been recruited when Butcher abruptly sticks him with a Compound-V injection sans consent.
A horrified Hughie is aghast at being forcibly prescribed this mystery substance, and temporarily leaves the Boys to decide whether he really wants to team-up with a man who'd take such despicable measures against supposed friends.